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Core Faculty

Edward Bahnson

Edward Moreira Bahnson, Ph.D.

edward_bahnson@med.unc.edu

Bahnson’s interest in diabetic vasculopathies is two-fold: understanding the difference in plaque progression and restenosis rates in the diabetic vs. non-diabetic environment. Bahnson’s long-term goal is to develop a specific targeted therapy for the vasculature to normalize the redox imbalance of the diabetic arteries.




Elena V Batrakova, Ph.D.

batrakov@email.unc.edu

The main focus of Batrakova’s research is to develop a CNS delivery system for antioxidants and neuronal growth factors to attenuate neuroinflammation and produce neuroprotection in patients with neurodegenerative disorders, such as Parkinson’s and Alzheimer’s diseases. For this purpose, her group utilizes inflammatory-response cells, macrophages and monocytes that can migrate toward the inflammation site, cross the blood brain barrier, and release the preloaded drugs in the brain.




Dr. Desimone

Joseph M. DeSimone, Ph.D.

desimone@email.unc.edu

The recent breakthroughs in the DeSimone laboratories using specifically-designed materials for imprint or soft lithography have enabled an extremely versatile and flexible method for the direct fabrication and harvesting of monodisperse, shape-specific nano-biomaterials.




Zongchao Han, M.D., Ph.D.

zongchao@med.unc.edu

The Zongchao Han, Ph.D., M.D., laboratory is interested in developing gene therapies for retinal diseases. Han’s lab is particularly interested in understanding the gene expression patterns that are regulated by the cis-regulatory elements. Another interest of the Han laboratory is to produce a multifunctional NP carrier for specific and efficient gene/drug targeting.




Alexander Kabanov

Alexander V. Kabanov, Ph.D., Dr.Sci.

kabanov@email.unc.edu

Alexander “Sasha” Kabanov, Ph.D., Dr.Sci., is the Mescal S. Ferguson Distinguished Professor, the Director of the Center for Nanotechnology in Drug Delivery at the UNC Eshelman School of Pharmacy and the Director of the Carolina Institute for Nanomedicine at the University of North Carolina at Chapel Hill.




Melina Kibbe

Melina R. Kibbe, M.D.

melina_kibbe@med.unc.edu

Kibbe’s research interests focus on developing novel therapies for patients with vascular disease while simultaneously studying the mechanism of how these therapies impact the vascular wall.




Marina Sokolsky, Ph.D.

msokolsk@email.unc.edu

Sokolsky’s research interests focus on drug delivery, brain delivery, sustained release, polymeric micelles, exosomes, inorganic nano particles, surface engineering for selective cell targeting, and remotely actuated theranostic drug delivery systems.




Shaomin Tian, Ph.D.

smtian@email.unc.edu

Tian is a Research Assistant Professor in the Department of Microbiology and Immunology in the UNC School of Medicine and is a member of the DeSimone Research Group.




Nick Tsihlis, Ph.D.

nick_tsihlis@med.unc.edu

Nick Tsihlis’s focus is on developing and evaluating therapies for patients with vascular disease, as well as understanding the molecular mechanisms underlying how these therapies work.




Andrew Wang, M.D.

zawang@med.unc.edu

The central theme of Wang’s research program is to apply advances from other fields such as chemical engineering, materials science, biomedical engineering and nanotechnology, to the field of oncology.